A PATIENT-CENTERED APPROACH TO MANAGEMENT OF PATIENTS WITH TYPE 2 DIABETES MELLITUS

We report on the study of the ACE and TCF7L2 gene polymorphisms in Uzbek patients with type 2 diabetes mellitus (T2DM). In the patients, frequencies of negative genotypes of the genes above were found higher than in the apparently healthy ethnically matching subjects. The similar pattern was found among the diabetics with myocardial infarction in medical history. Multifactor estimation of myocardial infarction risk factors was performed resulting in generation of a calculator of myocardial infarction risk in Uzbek T2DM patients with due regard to genetic markers.