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Cancer and Intraepithelial Neoplasia-Tissue-specific apoptotic effects of the p53 codon 72 polymorphism
Journal: American journal of Dentistry and oral care (Vol.1, No. 1)Publication Date: 2018-11-23
Authors : AN Rosenthal;
Page : 1-3
Keywords : VIN; Vulval Cancer; P53; Polymorphism;
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Abstract
P53 codon 72 polymorphism was analysed in UK women with human papillomavirus (HPV)-associated vulval intraepithelial neoplasia and vulval squamous cell carcinoma. Arginine homozygotes were significantly less common in either group compared with controls. We conclude that the arginine polymorphism may confer protection against the development of HPV-associated vulval neoplasia.
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Last modified: 2018-12-15 19:30:25