MODERN PHARMACOTHERAPY METHODS FOR GENERALIZED EPILEPSY FORMS
Journal: European Journal of Research (Vol.11, No. 12)Publication Date: 2018-11-11
Authors : Khaidarov Nodirjon Kadirovich Khodjieva Dilbar Tadzhievna Khaidarova Dildora Kadirovna;
Page : 62-67
Keywords : epilepsy; seizures; rational polytherapy; antiepileptic drugs; ionotropic AMPA receptors.;
Abstract
Epilepsy is a chronic polyetiological disease, manifested by repeated unprovoked convulsive or other seizures, loss of consciousness and accompanied by changes in personality. Among the forms of epilepsy, one of the most common and dangerous forms are generalized seizures. In recent years, the concept of generalized epilepsy has undergone significant changes: focal features have been identified with generalized epilepsy and typical features of idiopathic generalized epilepsy with focal epilepsy.The incidence of epilepsy is 50-70 per 100,000 population, the prevalence is 5- 10 per 1000 people. It is believed that 1 seizure and more in life endure about 5% of the population. The prevalence of epilepsy among children is high and ranges from 0.3% to 2% in various age populations (0.7-1.0% on average).The basic principles of treatment of epilepsy: individuality of treatment; continuity and duration of treatment; the complexity of treatment (etiological, pathogenetic and symptomatic); continuity of treatment.
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