EMERGENCE AND MANAGEMENT OF DISEASE BURDEN OF MRSA; A REVIEW FOR THE GLOBAL CHALLENGES

MRSA is a major human pathogen responsible for wide spectrum of diseases, prefers to grown pH environment above 6.5.They can survive down to pH 5 for extended periods of time. However the limits of endurance can be stretched if the organisms are first adapted to moderate acid pH or any antibiotic stress. MRSA is one of the major resistant pathogen found in the much members and skin of around one third of the population. It is extremely adaptable to antibiotic pressure. MRSA is associated with a number of virulence factors, Over half a century; the medical practitioner?s gas relied on the antibiotics to treat many pyogenic infections as well as other diseases. Unfortunately the misuse, overdose and overuse of antibiotics have triggered an increasing quality, variety and proliferation of multi-drug resistant (super bug). And consequently particularly virulent strain of MRSA these virulence strain gas developed resistant to all types of antibiotics including the last resort vancomycine. Now this natural ability of bacteria to develop resistant has become alarming health concern. Alternative method of treating of these antibiotic resistant staphylococcus infections are current being explored. This study helps in knowing theoretical problems associated with the resistant organism and leads to the development of new drug or any antibiotic or inhibitors which counteracts MRSA infections. It is possible to use in the human being also as a Therapeutic agents.