EPIDEMIOLOGY AND PATHOLOGY OF PRIMARY CNS NEOPLASMS AT A TERTIARY CARE HOSPITAL IN EASTERN INDIA - A SINGLE INSTITUTIONAL RETROSPECTIVE STUDY

INTRODUCTION CNS tumours are rare neoplasms comprising 1-2% of all neoplasms. With availability of better pathological evaluation, the characterisation of CNS tumour histology has improved which has not been reflected sufficiently in the existing data registry systems. We, at a Tertiary Care Hospital, in Eastern India made an effort to evaluate the epidemiological and histopathological data of the patients presenting with primary CNS tumours. MATERIALS AND METHODS Records of patients having primary CNS neoplasms presenting between 1st January 2017 and 31st December 2017 were evaluated and the epidemiological factors and histopathological features were recorded. RESULTS Median age of presentation was 33 years with a Male to Female ratio of 2.36:1. Astrocytomas comprised 37.8% cases with a mean age of presentation of 29.38 years for Grade II and 35.67 years for Grade III. WHO Grade IV tumours comprised 32.43% of cases. Frontal lobe was the most common site(29.73%). CONCLUSION The findings of our study corresponded to the available Indian data. However the median age of presentation was lower compared to data available from developed countries. The mean age of presentation of GBMs was also lower compared to western data indicating a difference in proportion of primary and secondary GBMs.