A Validated RP-HPLC Method for Estimation of Telmisartan and Metoprolol in its Bulk Form

This method is used for the estimation of Metoprolol and Telmisartan present in dosage forms. Chromatogram was performed on Xbridge C18 (5u,4.6x250mm), with a mobile phase composed of methanol: water adjusted pH 3.5 with (58:42% v/v) at flow rate of 1mL/min. the identification was carried out at 224 nm. Parameters studied and reported as in ICH. The linearity range (60-140%) coefficients (0.999) and % recovery was found to be (98-102%).Retention time was (2.091) & (5.089). The test sample in all formulations were within in their label claims and this technique is used for analysis.