A Case of a Successful Gestation in a Patient with an Unclassified Transfusion Dependent Congenital Dyserythropoietic Anemia and Hemoglobinopathy

Congenital Dyserythropoietic Anemias are rare congenital disorders of in effective erythropoiesis, are rarely fatal in early childhood. With the advent of safe blood transfusions and iron chelation, individuals with CDA are surviving to reproductive years, and new challenges have surfaced regarding management of women with CDA during pregnancy. We present a case of a 30-year-old woman with a history of CDA and a comorbid hemoglobinopathy resulting in transfusion-dependent anemia and severe iron overload who delivered a baby after a full term pregnancy. The literature about CDA and hemoglobinopathy in pregnancy is not extensive; therefore management of this patient could only be accomplished through consultation with a multidisciplinary group of clinical experts. Our hope is that this case report may serve as a catalyst for further investigation into optimal management of patients with severe anemia and iron overload during gestation.