Hyperprogression after immunotherapy in HNC: literature review and our experience
Journal: International Journal of Radiology and Radiation Oncology (Vol.4, No. 1)Publication Date: 2018-08-23
Abstract
Checkpoint inhibitors demonstrate salutary anticancer effects, including long-term remissions. PD-L1 expression/amplification, high mutational burden, and mismatch repair deficiency correlate with response. Champiat et al for the first time described a small subset of patients that could actually have tumor growth accelerated when given PD1/PDL1-targeting agents [1].
Other Latest Articles
- A retrospective study of SPECT/CT scans using SUV measurement of the normal pelvis with Tc-99m methylene diphosphonate
- Breast conserving surgery and intra-operative specimen radiography: Margin assessment by the surgeon or the radiologist?
- Brief palliative radiotherapy course for advanced and incurable head and neck cancer
- The Need to Deepen the Abscopal Effect and Synergy among Radiotherapy and Immunotherapy
- A comparative evaluation of two head and neck immobilization devices using verification film for head and neck cancer patients receiving radiation therapy at Ocean Road Cancer Institute (ORCI) aero-digestive tract
Last modified: 2019-01-07 18:01:19