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Hyperprogression after immunotherapy in HNC: literature review and our experience

Journal: International Journal of Radiology and Radiation Oncology (Vol.4, No. 1)

Publication Date:

Authors : ;

Page : 001-002

Keywords : ;

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Abstract

Checkpoint inhibitors demonstrate salutary anticancer effects, including long-term remissions. PD-L1 expression/amplification, high mutational burden, and mismatch repair deficiency correlate with response. Champiat et al for the first time described a small subset of patients that could actually have tumor growth accelerated when given PD1/PDL1-targeting agents [1].

Last modified: 2019-01-07 18:01:19