The Relationship between Plasma Levels of Large Neutral Amino Acids and Leptin in Women with or Without Obesity
Journal: Archives of Preventive Medicine (Vol.1, No. 1)Publication Date: 2016-12-30
Authors : Ming Der Chen; Yuh Min Song;
Page : 001-003
Keywords : Branched-chain amino acids; Glutamine; Obesity; Ornithine; Taurine;
Abstract
Obesity, characterized as excessive fat accumulation, is caused by interactions of genetic, environmental, and lifestyle factors [1]. Obesity increases the risk of various diseases including type 2 diabetes mellitus. Insulin resistance, commonly occurring in obese subjects, is attributed to the defects in insulin action on mediating the metabolism of macronutrients in target tissues [2]. Insulin increases amino acids uptake and protein biosynthesis in a tissue-specific manner [3]. In turn, certain amino acids can mediate insulin secretion [4].
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