Isolated Conjugated Hyperbilirubinemia in Seriously Ill Children – Don’t Forget Sepsis!Journal: Open Journal of Pediatrics and Child Health (Vol.2, No. 1)
Publication Date: 2016-12-30
Authors : Anirban Mandal; Amitabh Singh;
Page : 010-012
Keywords : Cholestasis; Jaundice; Pediatric; Pneumonia; ARDS;
Background: Jaundice is frequently associated with extrahepatic systemic infections. The important causes include increased bilirubin levels due to hemolysis, hepatic dysfunction, reduced excretion and cholestasis. Sepsis induced cholestasis has a unique pathophysiologic basis. Although common in gram negative sepsis among neonates, the clinical features of sepsis induced cholestasis are not widely recognized older children.
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