Hyperparathyroidism and Asthenia. A New Deal?

The profile of primary hyperparathyroidism (PHPT) changed profoundly over the course of the twentieth century. The highly symptomatic forms reported in the 1960s have progressively been replaced by forms with few symptoms and in some cases totally asymptomatic forms. As of 1991, with the increasing frequency of these new forms, several consensus meetings designed to defi ne the criteria for stablishing theoperability of minimally-symptomatic hyperparathyroidism have been organized [1]. However, the criteria chosen are in some cases deemed too restrictive as they do not take into account general and neuro-psychic symptoms which are frequently associated [2].