A Facile Synthesis and Docking Studies of N-(3-(4-Chlorophenoxy)benzyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Journal: Chemical Methodologies (Vol.3, No. 3)Publication Date: 2019-05-01
Authors : Ravi Kumar Bommeraa; Ramchander Merugu; Laxminarayana Eppakayala;
Page : 354-361
Keywords : Pyrrole; Pyrimidine; Docking; Spectral analysis; Biological studies;
Abstract
A simple method was developed to synthesize N-(3-(4-Chlorophenoxy)benzyl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine by coupling 3-(4-Chlorophenoxy)phenyl)methanamine and 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine. The products have been obtained in good yields and were characterized by spectral analyses and finally, docking studies were carried out.
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Last modified: 2019-01-15 17:45:53