A Study on Profile of Allergens Sensitivity and Associated Factors in Naso-Bronchial Allergic Patients

Background: Prevalence of nasobronchial allergy is increasing globally. Several genetic, environmental and other associated factors are responsible for this increase. This study is designed to investigate profile of different allergens sensitivities and associated factors involved in the prevalence of naso-bronchial allergy. Methods: 4312 skin prick tests with 77 allergens in 56 patients of nasobronchial allergy were studied using parameters like age, temporal association between asthma and allergic rhinitis, most common type of allergens, age of onset, sex, residence and family history of atopy. Results: It was found that the age groups 12-40 years are more prone to nasobronchial allergy. 75% patients have shown temporal association between asthma and allergic rhinitis. Most common offending allergens were insects (33.3%), followed by pollens (30.3%), fungi (13.6%), dust (8.3%), non-juicy foods (6.8%), juicy foods (4.16%) and dander (3.03%). Males have shown more prevalence of nasobronchial allergy than that of the females. 32% patients have shown genetic disposition. Conclusions: Overall, this study unravels different associated factors and profile of allergens in patients’ of nasobronchial allergy which will be helpful in diagnosis, management and treatment of asthma.