Natural Honey Bee Venom for Tissue Expansion in Reconstructive Surgery

Background: Tissue expansion is one of effective weapon in reconstructive surgery field. But traditional tissue expansion needs much effort and associated by known complications. In this study, tissue expansion is obtained by natural honey bee venom. Material and Methods: Twenty patients suffering from lesions which needed to excise in different body area, were included in this study. The lesions sizes were varied from 2 × 3 cm to 4 × 7 cm in different parts of body. Bee sting was used to produce tissue expansion, one sting on both sides of lesion before excision by 24 to 48 hours. Local anesthesia was used to decrease pain sensation before bee sting by 30 minutes. Results: One bee sting was enough to produce tissue expansion in fine tissue of face. Two bee stings one on both longitudinal sides of lesion were enough to produce tissue expansion in other areas. Bee sting tissue expansion increases the tissue area by about 50%. All wounds after lesions excision were closed directly without any tension and healed well within 2 to 3 weeks. Conclusion: Tissue expansion by bee sting is easy, simple, safe, effective, and costless in moderate cases.