Toxicological Profile of Aluminium Sulphate and Effect on Protein Profile in Albino Rat

World is full of xenobiotic substances such as heavy metal, pesticide and other pollutic agents. Heavy metal is a metallic element of relatively high density greater than 4gm/cm3 or 5 times more greater than water and is toxic even at low concentration. Heavy metals occur as a natural constituent of earth crust, can be emitted into environment by both natural and anthropogenic causes. Major cause of emission is the mining operations. Predetermined doses of aluminium sulphate in acute (1d) and subacute (7, 14, 21, 28ds) treatments revealed significant increase in albumin and globulin. The results are encouraging and highlight the toxic profile of aluminum sulphate and its effect on protein profile in albino rat.