GENETIC BACKGROUND FOR THE DEVELOPMENT OF SEPSIS

The purpose of this literature review was to summarize the results of recent research on the genetic background for the development of sepsis. A total of 28 Russian- and English-language literature sources were analyzed. A focus was put on various types of single-nucleotide polymorphisms, the presence of which contributes to the development of sepsis. The results of the recent studies point at the existence of the connection between the genetic polymorphism of each person and the risk of sepsis development, as well as its severity and outcome. With information about the genetic characteristics of each person available, individual approaches to the treatment and prevention of sepsis are possible.