Emergent of Colistin Resistant Enterobacteriaceae carrying the mcr-1 gene among clinical isolates from patients in an Argentine hospital: Clinical and microbiological aspects
Journal: Global Journal of Infectious Diseases and Clinical Research (Vol.4, No. 2)Publication Date: 2018-08-28
Authors : J Nievas D Torres F Nicola P Bonvehí L Scocozza W Alcalá F Herrera S Relloso; J Smayevsky;
Page : 010-012
Keywords : ;
Abstract
The recent emergence of multidrug-resistant (MDR) or extremely drug-resistant (XDR) Gram-negative bacteria has renewed interest in colistin (Polymyxins, a family of cationic polypeptide antibiotics) as a last-resort in the treatment of severe bacterial infections [1,2], despite being a drug with potential serious adverse events (mainly high risk of nephrotoxicity) [3,4]. Acquired resistance to polymyxins is generally associated with chromosomal mutations [5,6].
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