A study of clinical findings among newly diagnosed TB patients who are diagnosed diabetics under medications

Background: Tuberculosis remains a leading cause of death globally. In 2014 there were an estimated 12.8 million new cases of tuberculosis worldwide. The incidence of tuberculosis is greatest among those with conditions impairing immunity such as HIV infection and diabetes. Type 2 Diabetes mellitus amongst Indians occur a decade earlier when compared to the western population. Indians have more abdominal obesity and the waist-hip ratio. Aim of the study: Clinical findings Among Newly Diagnosed Tb Patients who are diagnosed Diabetics under Medications. Materials and methods: 100 cases of newly diagnosed sputum positive pulmonary tuberculosis with diabetes were fitting the inclusion criteria admitted over the period of 2 years from 2016-2017. Subjects were selected from medicine ward, pulmonology ward andTuberculosis ward under DTC. The diagnosis of Pulmonary tuberculosis was made with clinical presentation and verification by detection of acid-fast bacilli under a microscope. Results: Among the study population, 33(33.00%) were smokers, 38 (38.00%) were alcoholics and 9 (9.00%) were habituated to pan chewing. Among the study population, 53 (53.00%) had dyspnoea, 41 (41.00%) had chest pain, 66(66.00%) had a loss of appetite, 60 (60.00%) had an evening rise of temperature, 81(81.00%) had a loss of weight, 32 (32.00%) had hemoptysis, 78(78.00%) had a cough. Conclusion: DM was associated with more symptoms but not with increased severity of TB and had a negative effect on the outcome of anti-TB treatment. The findings of this study underline the need to improve the care of patients with concomitant DM and TB, especially in developing countries. Therefore, we advocate screening patients with TB for DM, especially those aged >35 years. Prospective studies are needed to determine the effects of tighter glycemic control on TB treatment and outcome.