STUDY OF URINARY TRACT INFECTIONS IN TERTIARY CARE HOSPITAL EMPHASIZING ON BACTERIOLOGICAL PROFILE WITH ANTIBIOGRAM

The present study was carried out to analyse the culture reports 470 urine samples collected from symptomatic patients between 18 to 80 years from department of medicine, surgery and gynaecology from May 2017 to 0ctober 2017. All the samples collected during the above period were subjected for culture sensitivity as per standard methods. The most common infection encountered in clinical practice is urinary tract infection. Urinary tract infection can be caused by different microorganisms including bacteria, parasites, fungi and viruses which are the major causative organisms. Among these, bacteria account for more than 95% of Urinary tract infection cases. Escherichia coli is the commonest urinary pathogen accounting for over 80% of community acquired infection. In this study the most common pathogenic organism isolated was Escherichia coli 44(55.69%) followed by Staphylococcus aureus 20(25.31%) and Klebsiella species 11(13.92%) in both males and females. Escherichia coli were sensitive to nitrofurantoin, amikacin and piperacillin tazobactam in 35 (79.4%), 25(56.81%) and 18(40.95%) respectively. Similarly 16(80%) of Staphylococcal isolates were sensitive to nitrofurantoin 11(55%) to amikacin and 5(25%) to piperacillin tazobactam. Klebsiella isolates also showed highest sensitivity to nitrofurantoin and piperacillin tazobactam 7(63%) followed by ceftriaxone 6 ( 54%.) This study will help clinicians to choose the right empirical antibiotics, and they should take into account the local sensitivity and resistance patterns while prescribing empirical oral or intravenous antibiotics.