MTH Score- A Novel Scoring System to Risk Stratify Renal Transplant Cases and to Improve Outcomes Post Renal Transplant

Introduction: Kidney transplantation is the optimal treatment of ESRD. Maximum incidence of graft dysfunction is in the first year post transplant. Methodology: 410 cases of live donor renal transplant were studied in a period of 2 years. All recipients were followed for 1 year and their mean serum creatinine was considered to compare variables affecting the post transplant outcomes. We studied various pre and post transplant factors. Using these factors we made 3 score charts (pre transplant, post transplant and combined MTH score) by giving points in ascending order starting from one to each subgroup of the factors affecting transplant outcome. Maximum points were given to the category in the subgroup which has the best impact on the transplant outcome. We classified patients into low risk MTH group C (score >30), intermediate risk MTH group B (score 21-30) and high risk MTH group A (score 11-20). Results: 96.72 % recipients in MTH low risk group C had serum creatinine < two at the end of one year and had better graft survival as against 54.54% in MTH high risk group A. Conclusion: Thus MTH score can help risk stratify renal transplant cases and predict the outcomes in renal transplant cases. Also modifying the risk factors can help high risk cases to fall into low risk category and may improve post transplant graft survival rates in the first year.