Hypophosphatemia, a Common Complication after Kidney Transplantation

Hypophosphatemia is a common complication after successful kidney transplantation, occurring in 90% of patients at the beginning of the post-transplant period. The fibroblast growth factor 23 (FGF-23) levels play an important role in the pathogenesis of this complication. This phenomenon is usually limited to the early posttransplant period, but it may persist for more than 10 years. Today, it is still debatable whether or not a low phosphate level is an independent risk factor for any adverse outcome, or just a marker of other causes. We therefore investigated the prevalence and natural course of post-transplant hypophosphatemia in our center. Its relationship with long-term outcomes.