L-Carnitine and Cardiac Function in Chronic Hemodialysis

Carnitine supplementation has been accepted worldwide, as the treatment of secondary carnitine deficiency in the patients with chronic hemodialysis. However, the relationship between l-carnitine supplementation and the improvement of cardiac function in such patients has not been clarified clinically, although the positive relationship has been strongly speculated theoretically. In this mini-review, the pit-fall in past studies and the possibility of future clinical trial will be discussed.