Evaluation of the Anti-inflammatory Activity and Ulcerogenic Risk of Sarenta, an Ivorian Herbal Preparation

"Sarenta" is an Ivorian herbal preparation used for various purposes such its anti-inflammatory activity. On account of the ulcerogenic side effects of conventional anti-inflammatory drugs and in order to promote African traditional medicine, this study aimed to assess the anti-inflammatory activity and ulcerogenic risk of Sarenta.The anti-inflammatory activity was evaluated by measuring the decrease in carrageenan-induced paw oedema in rat in acute model by "Sarenta", then in sub-acute model by the decrease of the formation of granuloma induced by cotton pellets implanted subcutaneously in rats. Ulcerogenic risk was assessed by administering "Sarenta" alone to rats that were anesthetized 4 hours later. The ulcerogenic risk on gastric mucosa was evaluated and codified using a magnifying glass.