Brain Hemodynamics and Cerebrovascular Reactivity in Patients with Tension-Type HeadacheAffiliation
Journal: Journal of Neurological Research And Therapy (Vol.2, No. 4)Publication Date: 2018-09-27
Authors : Rizvan Ya. Abdullaiev; Valeriy I. Kalashnikov; Olena L Tovazhnyanska; Alexander N. Stoyanov; Oksana I. Kauk;
Page : 15-27
Keywords : Transcranial dopplerography (TCD); Doppler ultrasound; Phenibut (Noophen); Cerebral Hemodynamic; Tension–type Headache (TTH).;
Abstract
Introduction: Tension-type headache (TTH) is very common, with a lifetime prevalence in the general population ranging in different studies between 30% and 78%. TTH, divided into episodic and chronic types, introduced in the manual "International Classification of Headache Disorders"(ICHD-I), is of practical importance. Infrequent episodic headaches (no more than once a month) may not require drug therapy, but, on the contrary, frequent forms may require expensive treatment. Objective: To study the state of cerebral hemodynamics and cerebrovascular reactivity in patients with Tension-type headache and evaluate the efficacy of treatment with Phenibite using Doppler ultrasound. Materials and Methods: A retrospective analysis of the results of ultrasound dopplerography of the anterior, middle and posterior cerebral arteries (ACA, MCA and PCA), Vertebral and Basal (VA, BA) arteries was performed in 188 patients with TTH. Among them are infrequent episodic TTH - 68 (36,2%) patients, frequent episodic TTH - 64 (34,0%) patients, chronic TTH - 56 (29,8%) patients. The age of the subjects was 18-45 years, among them 85 (45.2%) men and 103 (54.8%) women. The maximum systolic velocity (Vs), the end diastolic velocity (Vd), the resistance and pulsativity indexes (RI, PI) in all vessels were determined. Patients were given consent to participate in the study.
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