Nanoderm Extracellular Matrix for Reconstructive Surgery Applications
Journal: Archive of Biomedical Science and Engineering (Vol.1, No. 1)Publication Date: 2015-12-31
Authors : Gabriel Molina de Olyveira Pierre Basmaji Ligia Maria Manzine Costa Gino Bruno Francozo José Domingos da Costa Oliveira;
Page : 021-024
Keywords : Bacterial cellulose (Nanoderm®); Natural nanocomposites; Tissue engineering; Vegetal stem cells;
Abstract
Introduction: Bacterial cellulose (BC) can be used in wide area of applied scientific, especially for tissue regeneration and regenerative medicine, lately, bacterial cellulose mats are used in the treatment of skin conditions such as burns and ulcers, because of the morphology of fibrous biopolymers serving as a support for cell proliferation, its pores allow gas exchange between the organism and the environment. Moreover, the nanostructure and morphological similarities with collagen make BC attractive for cell immobilization, cell support and Natural Extracellular Matrix (ECM) Scaffolds. In this scope, Natural ECM is the ideal biological scaffold since it contains all the components of the tissue.The development of mimicking biomaterials and hybrid biomaterial can further advance directed cellular differentiation without specific induction.
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