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Ruta graveolens Protects Against Isoniazid/Rifampicin-Induced Nephrotoxicity through Modulation of Oxidative Stress and Inflammation
Journal: Global Journal of Biotechnology and Biomaterial Science (Vol.2, No. 1)Publication Date: 2016-09-30
Authors : Ayman M Mahmoud Omnia E Hussein Mousa O Germoush;
Page : 008-013
Keywords : ;
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Abstract
Background and Aim Drug-induced nephrotoxicity is a renal dyfunction that arises as a result of exposure to nephrotoxic drugs. Anti-tuberculosis therapy can cause nephrotoxicity and permanent kidney damage. The current study was designed to evaluate the possible protective effects of Ruta graveolens L. leaves extract against isoniazid/rifampicin-induced nephrotoxicity in rats.
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