SYNTHESIS OF SOME DIAZINE AND TRIAAZOLE DERIVATIVES FROM FURFURAL
Journal: INTERNATIONAL JOURNAL OF RESEARCH -GRANTHAALAYAH (Vol.7, No. 4)Publication Date: 2019-04-30
Authors : Al-Ajely M.S Shaban I.M;
Page : 83-89
Keywords : Diazine; Triazine Derivatives; Synthesis; Furfural.;
Abstract
Heterocyclic compound are important class of organic chemistry due to their wide spread in nature and there is versatile ways to synthesize them and also many site are available of functionalization for a given structure. Different metabolic pathways of heterocyclic compounds associated with living organism encouraged researchers to introduce different ways for synthesizing these types of compounds ,These researchers spent much efforts to design these types of compounds as drugs[1- 4].Since drugs needs to reach the target at certain time to penetrate through body tissue without interference with other cells and maintain it's does through this pathway. Accordingly, heterocyclic compounds were found to be used for many biological, clinical and pharmaceutical applications [5-7]. Furfural for example 2-(2-furyl) [1,3] dioxane,5-nito(1,3-imidazolyl-2,5-dion)- 3-yl furfurlidine was found to be used for treatment of urinary tract [8-10] also furfural derivatives were used for different biological applications[11,12] It was also known that many triazoles and diazines compounds were synthesized from different routes[ 13-16 ] . Some heterocyclic
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