Mitochondrial Dysfunction in Skin and Ocular Surface Disease: An Interdisciplinary Review | Biomed Grid
Journal: American Journal of Biomedical Science & Research (Vol.1, No. 4)Publication Date: 2019-02-22
Authors : Omeed M Memar Benjamin Caughlin; Ali Djalilian;
Page : 173-179
Keywords : Mitochondrial dysfunction; Ocular surface; Keratoconus; Cornea; Tear; Mitophagy; autophagy; Biomed Grid;
Abstract
Mitochondria are subcellular organelles that are the power-house of the cell. However, we now see that they play an ever-growing role in health, disease and aging of the skin. Not only does thee mitochondria produce the most reactive oxygen species (ROS) in the cell, but it affects major inflammatory and dysplastic processes. We have reviewed the literature of mitochondrial dysfunction and ocular surface disease. We have presented syndromes and non-syndromic conditions where mitochondrial dysfunction affects ocular surface health and dry eye, dry keratoconjunctivitis
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Last modified: 2019-05-13 13:48:42