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Natriuresis does not account for urinary concentration inhability in the chronically undernourished rat

Journal: Agrarian Academic Journal / Revista Agraria Academica (Vol.1, No. 1)

Publication Date:

Authors : ; ; ;

Page : 84-91

Keywords : Undernutrition; glomerular filtration rate; sodium balance; urinary concentration;

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Through different concentrations of sodium in the diet, we investigated whether the natriuresis observed in the DBR rats since weaning resulted from the higher Na + intake or from its lower conservation by the kidney and its effect on the urinary concentration. For this purpose, we used a multicentre diet, locally called the regional basic diet (DBR) and 60 male Wistar rats, treated from weaning with: (i) control diet, by the American Institute of Nutrition (AIN); ii) DBR supplemented with low Na + content (0.06%), the DBR group; (iii) DBR supplemented with normal Na + content (0.3%), the DBRnorm group; iv) DBR supplemented with high Na + content (3.12%), the DBRhiper group. The excretion capacity in relation to sodium intake was similar between these two groups (99.01 ± 0.12 vs 99.02 ± 0.17%). Malnutrition compromised the urinary concentration mechanism.

Last modified: 2019-05-14 02:58:51