A CASE REPORT OF EXTRAPONTINE MYELINOLYSIS IN A PATIENT WITH ADDISON'S DISEASE

Osmotic demyelination syndrome can occur as a complication of therapy of chronic hyponatremia. Isolated extrapontine myelinolysis occurring in patients with hypoadrenalism has been quoted in the literature only rarely. Here, we present a patient with addisons disease who developed extrapontine myelinolysis during his recovery from his primary illness. He developed features of basal ganglia involvement as the manifestation of extrapontine myelinolysis. Our patient developed this complication when he was treated with iv fluids for his vomiting and dehydration. He developed parkinsonian features following the intravenous fluid therapy. The safe rate of correction of hyponatremia has not been accurately determined. The prognosis of this condition varies considerably, either complete recovery or mortality