Sino-nasal T/NK lymphomas (Medio-Facial Malignant Granulomas)| Biomed Grid

Nasal T / NK Lymphoma Was First Described In 1933 As A Medio-Facial Malignant Granuloma. The Diagnosis of This Rare Disease Is Clinical and Immuno-Histopathological. We Report 18 Cases of TNK Lymphoma Collected at ENT and Maxillo-Facial Surgery Department Of La Rabta Hospital Over A Period Of 17 Years (2000-2016). We Included in This Work All Patients Whose Diagnosis of TNK Lymphoma Was Confirmed Histologically and By an Immuno-Histochemical Study. The Classification Adopted Was That of The World Health Organization (WHO) For Lymphoma (2008). The Treatment Was Based on Exclusive Radiotherapy for Four Patients Classified Stage IE, Radio-Chemotherapy for Five Patients: All Classified Stage IE Diffuse, And One Patient Classified Stage IV. Exclusive Chemotherapy Was Performed in Four Patients: Classified Stage IIE In Three Cases and Stage IE Diffuse in One Case. The Mean Follow-Up of Our Patients Was 8 Months (2-42 Months). Clinical Remission Was Noted Only in Two Patients