Echinchrome Pigment Isolated from Sea Urchin Improves Female Rat’s Fertility| Biomed Grid

Background: Echinochrome (Ech) is natural product pigment found in sea urchin. The present study aimed to evaluate effect of Ech on fertility of female rats. Methods: 18 virgin females will assign into 3 groups: Control; received 1 ml 2% DMSO (orally) daily for 30 days, Low dose Ech; received 1 ml of 0.1 mg/kg and high dose Ech; received 1 ml of 1 mg/kg Ech Results: High dose of Ech caused significant decrease in levels of glucose, AST, ALT, ALP, Creatinine, Urea, Uric acid, TC, LDL-C, Tg, while TP and albumin and HDL-C increase. Significant increase in FSH, LH, Uterus weight, Body weight gain, Placenta weight, Embryos number, Embryos weight, Embryo length was noticed after treatment with high dose of Ech. Conclusion: Echinchrome ameliorate female rats' fertility through an improvement in sex hormones, lipid profile, glucose level, liver function and kidney functions.