Antibiotic Resistant Infection of the Bacterial Group ESKAPEJournal: Scientific Journal of Medical Research (Vol.2, No. 8)
Publication Date: 2018-12-01
Authors : Dunea W. Khaled Basima A. Abdullah;
Page : 166-171
Keywords : ESKAPE; Antibiotic-resistant; HAIs; Mosul; Duhok;
Objectives: The antibiotic resistant infection of six bacterial species have been designated as 'Red Alert' human pathogens, which are responsible for 2/3 of all hospital acquired infection, they are grouped under acronym ESKAPE which include: 1- Enterococcus faecim or faecalis, 2- Staphylococcus aureus, 3- Klebsiella pneumoniae, 4- Acinetobacter baumannii, 5- Pseudomonas aeruginosa, 6- Enterobacter spp. For the first time as group in Mosul and Duhok / Iraq. Methods: Three hundred and thirty-two samples from different sources as Urine, Blood, Wounds, Burn, High Vaginal Swab (H.V.S.), Throat infection, Nose infection, Cerebrospinal fluid (C.S.F.) and Sputum were collected from hospital patients in city of Mosul and Duhok in Iraq. These samples were cultured on blood and Macconkey's agar. The bacterial colonies were purified and identified to species level using morphological, Biochemical tests , API and confirmed by Vitek 2 System and antibiotic sensitivity was carried out using Vitek 2 System. Results: Our results showed that 73 isolates 21.98 % were gave growth only and 34.25 % were gram positive and 65.75 % were gram negative and the most isolated number from burns 50 % and the lowest isolated number from C.S.F. 7.69 %. Fourty eight species were Kleb. pneumoniae(13), A. baumannii(12), Pseudo. aeruginosa(11) and E. cloacae(12) and Twenty five species were Staph. aureus(17) and E. faecalis(8). The result also showed the most bacterial species within ESKAPE group were resistant for almost antibiotics used under study. Conclusion: We were isolated ESKAPE bacterial species from acquired hospital infection and they comprise the majority of antibiotic resistance seen in hospital which diagnosed them by Vitek 2 System.
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