Reducing Adverse Reactions to Eradication of Helicobacter PyloriHelicobacter Pylori| Biomed Grid

During the eradication of Helicobacter pylori in patients, many adverse reactions inevitably occur due to the variety of drugs used and the relatively long course of treatment. Mild to moderate adverse reactions even account for many patients, and severe adverse reactions also account for some patients. In view of this situation, this article elaborates how to reduce adverse drug reactions from the following aspects. Of course, since the purpose of using drugs is to eradicate Helicobacter pylori, we should consider reducing adverse drug reactions without reducing the eradication rate. Appropriately shorten the course of treatment phase. Adverse reactions of drugs are related to the length of time they are used. The side effects of prolonging the use of drugs increase correspondingly. Of course, too short course of treatment also affects the eradication rate of Helicobacter pylori. Many literature studies show that the eradication effect of the 10-day course of treatment is similar to that of the standard regimens, while the adverse reactions are significantly reduced. Reduce the dosage of certain therapeutic drugs. Studies have shown that the use of half of amoxicillin, clindamycin or two-thirds of metronidazole and furazolidone for eradication treatment can reduce adverse reactions of patients, while the eradication rate of Helicobacter pylori has not significantly decreased. In addition, the effect of standard dose rabeprazole in eradication treatment was similar to that of double dose rabeprazole.