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Synthesis and characterization of some polymer derivatives of carvacrol as drug delivery system
Journal: Iranian Chemical Communication (Vol.4, No. 2)Publication Date: 2016-04-01
Authors : Mohammad Galehassadi; Ebrahim Rezaii;
Page : 165-174
Keywords : carvacrol; oregano; silyl ethers; copolymer; drug delivery;
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Abstract
Carvacrol is one of the main components of the EO of some Labiatae (Laminaceae) members like oregano, thyme and savory. Carvacrol has a lot of health benefits for example, antibacterial, and antioxidant activity.We synthesized some silicon derivatives of carvacrol, and characterized them by standard methods. Then the monomer of dimethylvinylsilyl carvacrol was synthesized. Copolymer of this monomer and methacrylic acid (MAA) was synthesized with different ratios. And releases of these polymers as an drug delivery systems were investigated in the pH = 1 pH = 7.4.In this way , we stnthesized a new sily polymer with base of drug delivery system for a phytochemical compound.
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