Synthesis and characterization of new (2E,2'E)-3,3'-(((3-hydroxypropane-1,2-diyl)bis(oxy))bis (2,1-phenylene))bis(1-phenylprop-2-en-1-one) and its transformation into 2,3-bis(2-(1,3-diphenyl-4,5-dihydro-1H-pyrazol-5-yl)phenoxy)propan-1-ol
Journal: Iranian Chemical Communication (Vol.5, No. 1)Publication Date: 2017-01-01
Authors : Alireza Banaei; Soheyla Karimi; Somayeh Minaei; Eslam Pourbasheer;
Page : 1-6
Keywords : Synthesis; bischalcone; bispyrazoline; bisaldehyde;
Abstract
In this paper, new (2E, 2'E)-3, 3'-(((3- hydroxypropane-1, 2-diyl) bis (oxy)) bis (2, 1-phenylene)) bis (1-phenylprop-2-en-1-one) (2a) was prepared in good yield by condensation reaction of acetophenone with bisaldehyde (1a) in ethanolic NaOH solutions at room temperature. The (2E, 2'E)-3, 3'-(((3- hydroxypropane-1, 2-diyl) bis (oxy)) bis (2, 1-phenylene)) bis (1-phenylprop-2-en-1-one) (2a) was immediately reacted with phenyl hydrazine under refluxing conditions in the presence of potassium hydroxide to obtain the corresponding 2, 3-bis (2-(1, 3-diphenyl-4, 5-dihydro-1H-pyrazol-5-yl) phenoxy) propan-1-ol (3a). The newly synthesized compounds confirmed by melting point and TLC and their structure were established by various analytical techniques such as IR, 1H-NMR, 13C-NMR and elemental analysis.
Other Latest Articles
- Experimental study of the effect of undoped ZnO, Fe and Mn doped ZnO nanostructures and the electrochemical response of the nanostructured modified carbon paste electrode toward Levodopa
- Fe3O4@silica sulfuric acid nanoparticles as a potent and recyclable solid acid catalyst for the synthesis of indole derivatives
- Prediction of boiling point and water solubility of crude oil hydrocarbons using sub-structural molecular fragments method
- Synthesis of nanostructured palladium, palladium oxide and palladium-palladium oxide nanocomposite by the gel combustion method and application as catalyst of hydrogen release
- A novel and efficient synthesis of bisindolyl methanes with using silica-supported 3-(triethoxysilyl) propane-1-ammonium chloride as reusable catalyst under solvent free conditions
Last modified: 2019-06-26 14:19:04