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Physico-chemical evaluation of a biocompatible microemulsion system containing IPM/Tween80/Isobutanol

Journal: Iranian Chemical Communication (Vol.7, No. 2)

Publication Date:

Authors : ; ;

Page : 134-141

Keywords : Microemulsion vehicles; phase diagram; viscosity; density; conductivity;

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Abstract

A biocompatible microemulsion system comprising of isopropyl myristate (IPM) as oil, tween 80 as a non-ionic surfactant and isobuthanol as co-surfactant was studied experimentally at 298.15 K. The pseudo-ternary phase diagram for the microemulsion system has been delineated at different surfactant to co-surfactant mass ratio of 1:1, 2.4:1 and 4:1. Some physico-chemical properties such as density, viscosity, refractive index, conductivity and pH, for a typical surfactant to co-surfactant mass ratio of 2.4:1 were determined precisely. It is verified that the transition point of viscosity, conductivity, refractive index and density occurs at about 30 wt% of water. The transition point could be attributed to either the change in the shape of droplets or the transition from o/w microemulsion phase to bicontinuous phase.

Last modified: 2019-06-26 14:29:13