Comparative Evaluation of Total Phenolics, Total Flavonoids Content and Antiradical Activity in Six Selected Species of Family Rosaceae Using Spectroscopic Method| Biomed Grid
Journal: American Journal of Biomedical Science & Research (Vol.3, No. 4)Publication Date: 2019-06-14
Authors : Kiran Zahid Maqsood Ahmed; Farah Khan;
Page : 352-357
Keywords : Polyphenolics; Flavonoids; Half maximal inhibitory concentration (IC50); Phytomedicine; Biomed Grid;
Abstract
The current study aims to investigate the total phenolics, total flavonoids content in addition to radical scavenging activity in six selected species of Family Rosaceae. Double Maceration Technique was adopted for extraction process. Results indicated the presence of phytochemicals in three species i.e. Pyrus communis, Prunus armeniaca & Malus pumila while absence of alkaloids and terpenoids was reflected in other three species i.e. Prunus persica, Prunus domestica & Fragaria vesca. Maximum Phenolic and flavonoids content was found in Fragaria vesca (leaf) using 70% ethanol as a solvent. All the tested plant species exhibited DPPH anti-radical properties however Prunus domestica (Leaf) 96.06±0.57 possessed maximum antioxidant potential with IC50 value of 0.236±0.001 mg/mL using Graph pad Prism 5.04 software. Ethanolic extracts gave preferable results and have the potential in extracting phytochemicals; these phytochemicals played tremendous role in treating multiple disorders including anticancer, antidiabetic and neurological disorders like Alzheimer or Dementia
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