STRUCTURES LUTERGININA

In this work, we studied the IR, UV, PMR and mass spectra, chemical transformations of lutherginin and its derivatives of homoproporphine alkaloids of time-lapse. According to the given spectral data, this compound is assigned to the homoproporphine base group with a spiro cyclohexanol ring. When establishing the structure of luterginine, its various spectral data and numerous chemical transformations were studied. The most important of them can be considered following with the action of acetic anhydride and acetic acid sodium from the base obtained O, N-diacetyl derivative, indicating the presence in it of a hydroxyl group and tetrahydroisoquinoline core. Heating of loterinin acid solutions led to the formation of α-diketone, the structure of which is confirmed by the preparation of dioxime. In the reaction of acetalization of the base, ketal was obtained. The reduction of loterninin hydrazine by hydrate forms a pyrazalin derivative, which undergoes catalytic decomposition and is converted to a compound containing a cyclopropane ring in its structure. It was found that their samples mainly differ in the composition of the strong base fractions