CYTOMEGALOVIRUS (CMV) INFECTION. NEW IN THE ETIOLOGY OF CHRONIC ABAC-TERIAL PROSTATITIS

The aim of the study was to define the role of cytomegalovirus infection as an etiological factor of chronic abacterial prostatitis and to create an algorithm for examining patients with chronic abacterial prostatitis of viral etiology. Forty five men aged 32-52 have been examined. Based on a comprehensive survey, all patients were diagnosed with chronic abacterial prostatitis. In all cases, the diagnosis of CPPS IIIB was established. To confirm the viral etiology of chronic abacterial prostatitis, patients were given additional specific examination. The essential role in the diagnosis was given to a complex specific laboratory examination: the determination of serological markers (antibodies (Ig) of the IgM and IgG class by the ELISA method) and virological (DNA viruses in prostate secretion and ejaculate by PCR method). To establish the prescription of infection, the avidity index (IA) of IgG antibodies was determined. According to the results of the examination, 16 patients were diagnosed seronegative. Of all the seropositive 29 patients, highly-enigmatic IgG to CMV was detected in 28 patients, which was 96.5%. In 1 patient, IgM was detected to CMV, which in accordance was 3.4%. The virus DNA was de-tected in 5 seropositive patients, which was 17.2%. In most cases, according to the study, the chronic form of cytomegalovirus infection predominates. Taking into account the data obtained, an algorithm for examining patients with suspected cytomegalovirus etiology of chronic abacterial prostatitis is proposed. The main crite-rion for the diagnosis of chronic abacterial prostatitis cytomegalovirus etiology is the detection of DNA virus in the secretion of the prostate and ejaculate by polymerase chain reaction. The viral etiology of chronic abacterial prostatitis is a modern prospective of searching for new diagnostic methods and etiopathogenetic treatment of this pathology. However, this problem requires further in-depth study and research.