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Human Identification by Amelogenin Test in Libyans| Biomed Grid

Journal: American Journal of Biomedical Science & Research (Vol.3, No. 6)

Publication Date:

Authors : ; ;

Page : 543-549

Keywords : Amelogenin; Libyans; Biomed Grid;

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Sex typing is essential in medical diagnosis of sex-linked disease and forensic science. Gender for criminal evidence of offender is usually as the initial information for investigation. For individualization, identification of gender is performed in addition to the STR markers recently. We reported the anomalous amelogenin results of 2 male samples (out of 238 males) represented as females (Y deletions) and another 2 samples with (X deletions) in Benghazi (Libya). The frequency in both was about 0.8%. Higher than those of the other populations reported. To confirm amelogenin results of the controversial samples, DNA was further used in SRY and Y-STR typing. All samples typed as males but two showed with X chromosomes. From the results, it was highly suggested that for the controversial cases of human gender identification with amelogenin tests, amplification of SRY gene or/and Y-STR markers will be adopted to confirm the gender [1

Last modified: 2019-07-23 14:38:31