Soft Drinks Associate with Low Levels of Some Bone and Infertility Markers in Women

The consumption of soft drinks has increased drastically over the decades; important concerns raised are the medical and health implications of the increased consumption. We aimed to assess the effect of soft drink consumption on the serum levels of some bone and infertility markers in women. The biochemical investigations for serum calcium and phosphorus concentrations was carried out with Random Access Biochemistry auto-analyzer (KENZA 240 TX) using Bio-Labo diagnostics kits, while serum hormonal levels; prolactin, Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), progesterone, estrogen and vitamin D were assayed using Abbot Architect i1000 SR (USA) reagents. A total of 128 newly diagnosed women with primary infertility were screened; out of which 112 (87.5%) consumed soft drinks while 16 (12.5%) do not. Sixty-eight (53.1%) participants consumed more than 4 bottles per day and orange soft drinks happens to be the drink of choice for 40 (31.2%) participants. A significantly high level of serum inorganic phosphate (P < 0.05) in subject that consumed soft drinks was observed. Serum levels of calcium and vitamin D showed no significant difference (P > 0.05) with consumption. Serum level of progesterone was observed to be significantly (P < 0.05) low in subjects consuming soft drinks. Consumption of soft drinks might be associated with high inorganic phosphates and reduced serum level of serum progesterone.