RADIOLOGICAL IMAGING IN A PATIENT WITH COMPLETE ANDROGEN INSENSITIVITY SYNDROME

Androgen insensitivity syndrome (AIS), initially referred as the testicular feminisation syndrome, results from end-organ resistance to testosterone. It is classified into complete (CAIS), partial (PAIS), or mild (MAIS) with different radiological imaging findings in all of them. Complete androgen insensitivity syndrome(CAIS) is an X-linked recessive androgen receptor disorder which is characterized by a female phenotype with an male (XY) karyotype. Individuals have normal female external genitalia but absence of the Mullerian duct derivatives, (i.e) absence of Fallopian tubes, uterus, cervix, and the proximal part of the vagina , with presence of intraabdominal, labial, or inguinal testes. The estimated prevalence of this syndrome is between 1 : 1,00,000. Radiological imaging is important both to diagnose and also to localize the gonads prior to surgical treatment. In this paper, we present a case of complete androgen insensitivity syndrome in adult women who presented with complaints of primary amenorrhea and infertility.