The Application of Arylglyoxals in the Synthesis of Pyrrolo[2,3-d]pyrimidines via Multicomponent Reactions
Journal: Journal of Chemical Reviews (Vol.1, No. 3)Publication Date: 2019-07-30
Authors : Ramin Javahershenas; Jabbar Khalafy; Rolf Herman Prager;
Page : 233-242
Keywords : Arylglyoxals; Pyrrolo[2; 3-d]pyrimidines; Multicomponent reactions; Enamines;
Abstract
This review provides an overview of the recent literature on application of arylglyoxals the synthesis of pyrrolo[2,3-d]pyrimidines via multicomponent reactions in the period of 2008–2018. 1,2-Dicarbonyl compounds are attractive precursors for synthesis of various heterocyclic compounds, and arylglyoxals are frequently applied in synthesis of various organic compounds, and in particular of pyrrolo[2,3-d]pyrimidines derivatives, which are important due to their biological and pharmaceutical activities.
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Last modified: 2019-08-03 17:06:57