Outbreak of enzootic ataxia in lambs in the semi-arid state of Pernambuco, Brazil

An outbreak of delayed enzootic ataxia in lambs in southern in the southern semi-arid state of Pernambuco. Affected lambs (n=18) showed symptoms of ataxia of the hind limbs, as well as difficulty in getting up and inability to walk, with a "dog sitting" posture. Histopathological examination of the spinal cord revealed vacuolization, axonal spheroids and myelin remains phagocytosed by macrophages and demyelination of the white matter. Low serum concentration of copper (6.88 μmol/L) was observed. Serum iron, zinc and molybdenum concentrations were at normal levels for the species. Clinical and laboratory data allowed concluding diagnosis of primary enzootic ataxia.