The Placental Villi During Chronic Hypertension

Two placentas obtained of woman pregnancy at 32 at 39 years old with gestational ages of 37 and 41 weeks of pregnancy were classified as P1 and P2 respectively. Patient P1 with history clinic of three gestations, two caesarian, one abortion and 117 Kg of weight and P2 with seven gestations, 67 Kg of weight, without that history. Specimens were fixed and processed according H&E stain and the degenerative changes in the placental villi observed with light microscopy. Observations were done in base at necrosis, immaturity, fibrinoid change, edema, hemorrhage, infarcts, chorangiosis, syncytial knots, calcification, fibrosis, polymorphonuclears, changes in the wall of the vessels and intervillous thrombosis. P1 showed degenerative changes in syncytium and stromal region with increased deposition of fibrinoid, edema, tissue death, vessel-contraction, chorangiosis, calcification, infarcts and destruction of the organization of the villi. P2 with dilatation of vessels, infarcts, stem villi with degenerative changes in syncytium and stroma, edema and contracted vessels. Terminal and intermediate placental villi were seen destroyed and erythrocytes are expelled to the intervillous space. Chronic hypertension has provoked severe degenerative changes to the placental villi disorganizing the placental structure with high risk of the good fetal development.