Central line blood stream infection in intensive care unit: Importance of the care bundle

Ntroduction: Blood stream infections (BSIs) due to central venous catheterization are one of the major device-associated infections in the ICU. It can be a source of dangerous sepsis, bacteremia, multi organ failure and even death1 Objective: To determine the rate of central line associated blood stream infection (CLABSI), incidence rate and antibiotic sensitivity pattern of isolated organisms. Materials and Methods: Central Line and Peripheral line blood samples were collected with proper aseptic precautions. After collection, blood samples were placed in BacT/ALERT 3D and Vitek 2 automated system for identification and their antibiotic sensitivity pattern. Results: Out of 95 Central Line and Peripheral line blood samples, 30 culture were identified as blood stream infections, among them 14 have CLABSI. CLABSI rate in our study is 11 per 1000 catheter days. Coagulase negative staphylococci was the commonest organism isolated in the current study those were about 6(43%). Second most common organism was Klebsiella pneumoniae 4(29%) followed by Pseudomonas aeruginosa 3(21%) and Candida albicans 1(7%). Conclusion: Central line blood stream infection, most commonly caused by colonization and duration of catheterization. Septicemia and multi organ failure may occur because of CLBSI.