Vitamin d deficiency in psoriatic patients -A case control study
Journal: IP Indian Journal of Clinical and Experimental Dermatology (IJCED) (Vol.5, No. 1)Publication Date: 2019-03-27
Authors : Rishi Hassan Febin Kallan Siva Subramanian Rathish T Pillai Athira Dinachandran;
Page : 37-40
Keywords : Psoriasis; Autoimmunity; Psoriasis Area and severity index; 25-hydroxy vitamin D.;
Abstract
Introduction: Many studies have shown that vitamin D deficiency have been associated with multiple autoimmune conditions like psoriasis, rheumatoid arthritis, diabetes mellitus. Objective: The main purpose of this study was to analyze vitamin D status of psoriasis patients in comparison to healthy controls. Materials and Methods: The study comprised of 50 (30 male & 20 female) clinically confirmed cases of chronic plaque psoriasis of age group (20-60 years) attending outpatient department of Dermatology, venereology, leprosy, Vinayaka Mission's Medical College & Hospital, Karaikal from 2012 to 2014.At the same time 50 healthy individuals without psoriasis were also investigated (age & sex matched). Results: The mean serum 25-OHD levels in psoriatic patients and controls were 22.308+_2.974 and 33.726 +_2.688 ng/ml respectively. The difference was statistically significant (P=<0> Limitations: Additional studies with bigger numbers of patients are essential to evaluate the pathogenic mechanisms associated with psoriasis and vitamin D.
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