A comparative study of hyperbaric ropivacaine with fentanyl and hyperbaric bupivacaine with fentanyl in intrathecal block for perineal surgeries: A prospective randomized double blind clinical study

Introduction: To compare the clinical effects of intrathecal 2.5ml of Hyperbaric Ropivacaine with Fentanyl and 2.5ml of Hyperbaric Bupivacaine with Fentanyl in patients undergoing various perineal surgeries. Materials and Methods: After meeting the inclusion criterias 120 patients belonging ASA physical status 1 & 2, were divided in to two groups of 60 each. Randomization was done by computer generated randomization table. Group B patients received 2.5 ml solution, which was prepared from 3.5ml 0.5% hyperbaric Bupivacaine (5 mg/ ml) along with 0.5 ml Fentanyl (25µg/ml). Group R patients received 2.5 ml solution, which was prepared from 2.5 ml of Ropivacaine (7.5 mg/ ml) along with 0.5 ml Fentanyl (25µg/ml). To make it hyperbaric 1 ml of 10% dextrose was added. Both the groups were studied for duration of sensory and motor blocks and hemodynamic variations. Results: Regression of sensory block to T 10 was statistically significant with group R (119±24 min) as compared to group B (153±21.3 min), P value being less than 0.001.Duration of regression of motor block to Bromage scale 0 was also statistically significant with group R (144.5±26.1 min) as compared to group B (181±21.3 min). P value being less than 0.001 degree of motor blockade was statistically significant with group R (80%) compared to group B (100%). Conclusion: Hyperbaric Ropivacaine with Fentanyl is a more suitable alternative to hyperbaric Bupivacaine with Fentanyl in perineal surgeries.