Central giant cell granuloma: Diagnostic difficulty and multi-stage treatment

The Central Giant Cell Granuloma or CGCG is a fibro-osseous lesion which is considered to be reactive in nature by many authors. Here we are attempting to report a case of CGCG which has been given combination therapy. The combination therapy included local infiltration of corticosteroids along with surgical enucleation of the lesion. The surgical therapy was done after 4 successful administrations of steroids intra-lesionally in clinically aggressive lesion of CGCG. The patient who had been treated by combination therapy has been symptom free from past 3yrs. This combination therapy is hence found to be of adequate success in treating these aggressive lesions which can be addressed without resection of the bone. The morbidity of treatment carried out hence could be reduced a ton. Thereby we are attempting to report and review the treatment protocol for management of such large giant cell lesions which are not so commonly seen in oral and maxillofacial region. The case reported here has been secondarily reconstructed with illiac crest grafting with adequate success.